rospedРоссийский педиатрический журнал имени М.Я. СтуденикинаM.Ya. Studenikin Russian Pediatric JournalФГАУ «НМИЦ здоровья детей» Минздрава России10.46563/1560-9561-2021-24-1-61-65rosped-1226Research ArticleКЛИНИЧЕСКИЙ СЛУЧАЙCLINICAL CASEПОЧЕЧНЫЙ ТУБУЛЯРНЫЙ АЦИДОЗ III ТИПА У ГРУДНОГО РЕБЕНКАA CLINICAL CASE OF RENAL TUBULAR ACIDOSIS (TYPE III) IN AN INFANThttps://orcid.org/0000-0002-6912-1471ХаритоноваНаталия АлександровнаKharitonovaN. A.kharitonovan@nczd.ruhttps://orcid.org/0000-0003-2075-6668БасаргинаМилана АлександровнаBasarginaM. A.basargina.ma@nczd.ruhttps://orcid.org/0000-0003-3131-331XАнаньинПётр ВладимировичAnaninP. V.ananin@nczd.ruhttps://orcid.org/0000-0001-9255-6927ЕвлоеваХадижат СаварбековнаEvloevaKh. S.evloeva1994maga@mail.ruФГАОУ «Национальный медицинский исследовательский центр здоровья детей» Минздрава РоссииNational Medical Research Center for Children’s Health2021140120252416165Copyright © Харитонова Н.А., Басаргина М.А., Ананьин П.В., Евлоева Х.С., 20252025Харитонова Н.А., Басаргина М.А., Ананьин П.В., Евлоева Х.С.Kharitonova N.A., Basargina M.A., Ananin P.V., Evloeva K.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.rosped.ru/jour/article/view/1226

Тубулопатия сопровождается дисбалансом электролитов из-за нарушения экскреции ионов водорода (I тип), нарушением обратного всасывания бикарбонатов (II тип), аномальной продукцией альдостерона или взаимодействия с ним (IV). Течение может быть бессимптомным или с проявлениями электролитных расстройств: слабостью, тошнотой, костными деформациями. Диагностика почечной ацидемии базируется на измерениях рН мочи и электролитов, данных генетических анализов. В статье описаны клиническая картина, классификация и диагностика казуистически редкого почечного тубулярного ацидоза III (комбинированного) типа у грудного ребенка, отражена значимость применения современных методов исследования для оптимизации своевременного лечения и улучшения качества жизни.

Tubulopathy is accompanied by electrolyte imbalance due to impaired excretion of hydrogen ions (type I), impaired reabsorption of bicarbonates (type II), abnormal aldosterone production, or interaction with it (IV). The course can be asymptomatic or with manifestations of electrolyte disorders: weakness, nausea, bone deformities. Diagnosis of renal acidemia is based on measurements of urine pH and electrolytes, data from genetic tests. A clinical case of renal tubular acidosis (type III) in an infant. The article presents the clinical picture of renal tubular acidosis, its classification, and diagnostics in children. Authors consider the importance of applying modern research methods to conduct timely treatment and improve the patients’ lives.

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