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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rosped</journal-id><journal-title-group><journal-title xml:lang="ru">Российский педиатрический журнал имени М.Я. Студеникина</journal-title><trans-title-group xml:lang="en"><trans-title>M.Ya. Studenikin Russian Pediatric Journal</trans-title></trans-title-group></journal-title-group><publisher><publisher-name>ФГАУ «НМИЦ здоровья детей» Минздрава России</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.46563/1560-9561-2022-25-5-333-336</article-id><article-id custom-type="edn" pub-id-type="custom">pkxvxb</article-id><article-id custom-type="elpub" pub-id-type="custom">rosped-206</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>Особенности нутритивного статуса детей с позвоночно-спинномозговой травмой на ранних этапах восстановления</article-title><trans-title-group xml:lang="en"><trans-title>Features of the nutritional status in children with spinal cord injury at the early stages of recovery</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0060-7895</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Понина</surname><given-names>Ирина Витальевна</given-names></name><name name-style="western" xml:lang="en"><surname>Ponina</surname><given-names>Irina V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Врач педиатр отдела реабилитации ГБУЗ «НИИ неотложной детской хирургии и травматологии».</p><p>e-mail: ponina.irina@mail.ru</p></bio><bio xml:lang="en"><p>Pediatrician of the Rehabilitation Department of the Clinical and Research Institute of Emergency Pediatric Surgery and Trauma, Moscow, 119180, Russian Federation.</p><p>e-mail: ponina.irina@mail.ru</p></bio><email xlink:type="simple">ponina.irina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2258-2913</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Новосёлова</surname><given-names>Ирина Наумовна</given-names></name><name name-style="western" xml:lang="en"><surname>Novosyolova</surname><given-names>Irina N.</given-names></name></name-alternatives><email xlink:type="simple">i.n.novoselova@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1622-0169</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Валиуллина</surname><given-names>Светлана Альбертовна</given-names></name><name name-style="western" xml:lang="en"><surname>Valiullina</surname><given-names>Svetlana A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3235-8854</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ахадов</surname><given-names>Толибджон Абдуллаевич</given-names></name><name name-style="western" xml:lang="en"><surname>Akhadov</surname><given-names>Tolibdzhon A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4709-9461</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Божко</surname><given-names>Ольга Васильевна</given-names></name><name name-style="western" xml:lang="en"><surname>Bozhko</surname><given-names>Olga V.</given-names></name></name-alternatives><email xlink:type="simple">bozhko_olga@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лукьянов</surname><given-names>Валерий Иванович</given-names></name><name name-style="western" xml:lang="en"><surname>Lukyanov</surname><given-names>Valeriy I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4434-0659</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Попова</surname><given-names>Ольга Владимировна</given-names></name><name name-style="western" xml:lang="en"><surname>Popova</surname><given-names>Olga V.</given-names></name></name-alternatives><email xlink:type="simple">oglapopova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ «НИИ неотложной детской хирургии и травматологии»</institution></aff><aff xml:lang="en"><institution>Clinical and Research Institute of Emergency Pediatric Surgery and Trauma</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>14</day><month>09</month><year>2023</year></pub-date><volume>25</volume><issue>5</issue><fpage>333</fpage><lpage>336</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Понина И.В., Новосёлова И.Н., Валиуллина С.А., Ахадов Т.А., Божко О.В., Лукьянов В.И., Попова О.В., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Понина И.В., Новосёлова И.Н., Валиуллина С.А., Ахадов Т.А., Божко О.В., Лукьянов В.И., Попова О.В.</copyright-holder><copyright-holder xml:lang="en">Ponina I.V., Novosyolova I.N., Valiullina S.A., Akhadov T.A., Bozhko O.V., Lukyanov V.I., Popova O.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rosped.ru/jour/article/view/206">https://www.rosped.ru/jour/article/view/206</self-uri><abstract><sec><title>Введение</title><p>Введение. Позвоночно-спинномозговая травма (ПСМТ) запускает каскад метаболических реакций, приводящих к повышенному запросу в макронутриентах. Несвоевременная коррекция нутритивных потерь приводит к значимому снижению массы тела больного и увеличению числа алиментарно-зависимых осложнений.</p></sec><sec><title>Цель</title><p>Цель: определить особенности нутритивного статуса детей с ПСМТ на ранних этапах восстановления при реабилитации. </p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Наблюдали 50 детей в возрасте 7–17 лет с ПСМТ в 1-й месяц после травмы. Всем больным на протяжении 6 мес проводился мониторинг нутритивного статуса, включавший оценку антропометрических и лабораторных показателей, а также состояние компонентного состава плегированных конечностей с использованием МР-сканирования на высокопольном (1,5 Т) МР-томографе «Toshiba».</p></sec><sec><title>Результаты</title><p>Результаты. Установлено наличие риска развития нутритивного дефицита у всех больных с ПСМТ. У этих больных к 1-му месяцу с момента травмы развивается недостаточность питания, приводящая к тканевому дисбалансу мышц повреждённых конечностей. Своевременная коррекция нутритивных потерь с использованием специализированных смесей и продуктов стандартного рациона позволяет стабилизировать прогрессирующую потерю массы тела и избежать осложнений, связанных с недостаточной алиментацией.</p></sec><sec><title>Заключение</title><p>Заключение. Комплексный анализ нутритивного статуса является основой для определения адекватной нутритивной поддержки и диетологического сопровождения детей с ПСМТ.</p></sec><sec><title>Участие авторов</title><p>Участие авторов:Понина И.В. — концепция и дизайн исследования;Понина И.В., Новосёлова И.Н., Попова О.В. — сбор и обработка материала;Лукьянов В.А. — статистическая обработка материала;Понина И.В., Новосёлова И.Н. — написание текста;Ахадов Т.А., Божко О.В. — анализ результатов МРТ;Новосёлова И.Н. — редактирование;Валиуллина С.А. — общее руководство проведением исследования, редактирование, утверждение рукописи для публикации.Все соавторы — утверждение окончательного варианта статьи, ответственность за целостность всех частей статьи.</p></sec><sec><title>Финансирование</title><p>Финансирование. Исследование было поддержано грантом Правительства г. Москвы «Диффузно-тензорные изображения (ДТТ) и функциональная магнитно-резонансная томография (фМРТ) спинного мозга в клинической практике (норма и позвоночно-спинномозговая травма») (проект № 2112-9) и «Cистема комплексной реабилитации детей с острыми травматическими повреждениями на основе организационной модели с применением инновационных медико-конвергентных технологий» (проект № 2412-9). </p></sec><sec><title>Конфликт интересов</title><p>Конфликт интересов. Авторы заявляют об отсутствии конфликта интересов. </p></sec><sec><title>Поступила 05</title><p>Поступила 05.09.2022Принята к печати 20.09.2022Опубликована 31.10.2022</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Spinal cord injury, like any severe injury, triggers a cascade of metabolic reactions leading to an increased demand for macronutrients. Untimely correction of nutritional losses leads to significant weight loss in the patient, and as a result, to an increase in the number of alimentary-dependent complications.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The study included fifty spinal cord injury (SCI) children, aged of 7–18 years admitted to the Clinical and Research Institute of Emergency Pediatric Surgery and Trauma in Moscow within the first month after injury. All patients from the moment of admission and over the next 6 months had a dynamic monitoring of their nutritional status. It included examination of anthropometric and laboratory parameters, and examination of the state of component composition of plegic limbs using MR scanning on a high-field (1.5 T) Toshiba MR tomograph.</p></sec><sec><title>Results</title><p>Results. The screening performed has revealed a risk of nutritional deficiency in all SCI patients. The findings were obtained indicating that in the majority of children of this category significant malnutrition had developed by the first month after the injury. Subsequently, it caused tissue imbalance in muscles of the plegic limbs. The timely correction of nutritional losses with special mixtures and standard diet products has stabilized the progressive weight loss and prevented complications associated with insufficient alimentation.</p></sec><sec><title>Conclusion</title><p>Conclusion. A regular comprehensive assessment of nutritional status is the basis for determining adequate nutritional support and diet for SCI children.</p></sec><sec><title>Contribution</title><p>Contribution:Ponina I.V. — concept and design of the study;Ponina I.V., Novosyolova I.N., Popova O.V. — collection and processing of material;Lukyanov V.A. — statistical processing of the material;Ponina I.V., Novosyolova I.N. — writing text;Akhadov T.A., Bozhko O.V. — analysis of MRI results;Novosyolova I.N. — editing;Valiullina S.A. — general management of the study, editing, conclusion of the manuscript for publication.All co-authors — approval of the final version of the article, responsibility for the integrity of all parts of the article.</p></sec><sec><title>Acknowledgment</title><p>Acknowledgment. The study was supported by a grant from the Government of Moscow «Diffuse-tensor imaging (DTT) and functional magnetic resonance imaging (fMRI) of the spinal cord in clinical practice (normal and spinal cord injury») (project No. 2112-9) and «System of integrated rehabilitation of children with acute traumatic injuries based on an organizational model using innovative medical convergent technologies» (project No. 2412-9).</p></sec><sec><title>Conflict of interest</title><p>Conflict of interest. The authors declare no conflict of interest. </p></sec><sec><title>Received</title><p>Received: September 05, 2022Accepted: September 20, 2022Published: October 31, 2022</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>позвоночно-спинномозговая травма</kwd><kwd>дети</kwd><kwd>нутритивный статус</kwd><kwd>недостаточность питания</kwd><kwd>энтеральное питание</kwd></kwd-group><kwd-group xml:lang="en"><kwd>spinal cord injury</kwd><kwd>children</kwd><kwd>nutritional status</kwd><kwd>malnutrition</kwd><kwd>enteral nutrition</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Dijkink S., Meier K., Krijnen P., Yeh D.D., Velmahos G.C., Schipper I.B. Malnutrition and its effects in severely injured trauma patients. Eur J Trauma Emerg Surg. 2020; 46(5): 993-1004. https://doi.org/10.1007/s00068-020-01304-5</mixed-citation><mixed-citation xml:lang="en">Dijkink S., Meier K., Krijnen P., Yeh D.D., Velmahos G.C., Schipper I.B. Malnutrition and its effects in severely injured trauma patients. Eur J Trauma Emerg Surg. 2020; 46(5): 993–1004. https://doi.org/10.1007/s00068-020-01304-5</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Dipasquale V., Cucinotta U., Romano C. Acute Malnutrition in Children: Pathophysiology, Clinical Effects and Treatment. Nutrients. 2020; 12(8): 2413. https://doi.org/10.3390/nu12082413</mixed-citation><mixed-citation xml:lang="en">Dipasquale V., Cucinotta U., Romano C. Acute Malnutrition in Children: Pathophysiology, Clinical Effects and Treatment. Nutrients. 2020; 12(8): 2413. https://doi.org/10.3390/nu12082413</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Black R.E., Victora C.G., Walker S.P., Bhutta Z.A., Christian P., de Onis M., et al. Maternal and child undernutrition and overweight in low-income and middle-income countries. Lancet. 2013; 382(9890): 427-51. https://doi.org/10.1016/S0140-6736(13)60937-X</mixed-citation><mixed-citation xml:lang="en">Black R.E., Victora C.G., Walker S.P., Bhutta Z.A., Christian P., de Onis M., et al. Maternal and child undernutrition and overweight in low-income and middle-income countries. Lancet. 2013; 382(9890): 427–51. https://doi.org/10.1016/S0140-6736(13)60937-X</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Wang Y.J., Zhou H.J., Liu P.J., Liu G.L., Zheng Y., Wei B., et al. Risks of undernutrition and malnutrition in hospitalized pediatric patients with spinal cord injury. Spinal Cord. 2017; 55(2): 247-54. https://doi.org/10.1038/sc.2016.113</mixed-citation><mixed-citation xml:lang="en">Wang Y.J., Zhou H.J., Liu P.J., Liu G.L., Zheng Y., Wei B., et al. Risks of undernutrition and malnutrition in hospitalized pediatric patients with spinal cord injury. Spinal Cord. 2017; 55(2): 247–54. https://doi.org/10.1038/sc.2016.113</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Wong S., Derry F., Jamous A., Hirani S.P., Grimble G., Forbes A. The prevalence of malnutrition in spinal cord injuries patients: a UK multicentre study. Br J Nutr. 2012; 108(5): 918-23. https://doi.org/10.1017/S0007114511006234</mixed-citation><mixed-citation xml:lang="en">Wong S., Derry F., Jamous A., Hirani S.P., Grimble G., Forbes A. The prevalence of malnutrition in spinal cord injuries patients: a UK multicentre study. Br J Nutr. 2012; 108(5): 918–23. https://doi.org/10.1017/S0007114511006234</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Dawodu T.S., Scott D.D., Chase M. Nutritional management in the rehabilitation setting. https://doi.org/emedicine.medscape.com/article/318180-overview</mixed-citation><mixed-citation xml:lang="en">Dawodu T.S., Scott D.D., Chase M. Nutritional management in the rehabilitation setting. https://doi.org/emedicine.medscape.com/article/318180-overview</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Levine A.M., Nash M.S., Green B.A., Shea J.D., Aronica M.J. An examination of dietary intakes and nutritional status of chronic healthy spinal cord injured individuals. Paraplegia. 1992; 30(12): 880-9. https://doi.org/10.1038/sc.1992.165</mixed-citation><mixed-citation xml:lang="en">Levine A.M., Nash M.S., Green B.A., Shea J.D., Aronica M.J. An examination of dietary intakes and nutritional status of chronic healthy spinal cord injured individuals. Paraplegia. 1992; 30(12): 880–9. https://doi.org/10.1038/sc.1992.165</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Spungen A.M., Wang J., Pierson R.N. Jr, Bauman W.A. Soft tissue body composition differences in monozygotic twins discordant for spinal cord injury. J Appl Physiol. 2000; 88(4): 1310-5. https://doi.org/10.1152/jappl.2000.88.4.1310</mixed-citation><mixed-citation xml:lang="en">Spungen A.M., Wang J., Pierson R.N. Jr, Bauman W.A. Soft tissue body composition differences in monozygotic twins discordant for spinal cord injury. J Appl Physiol. 2000; 88(4): 1310–5. https://doi.org/10.1152/jappl.2000.88.4.1310</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Van der Scheer J.W., Totosy de Zepetnek J.O., Blauwet C., Brooke-Wavell K., Graham-Paulson T., Leonard A.N., et al. Assessment of body composition in spinal cord injury: A scoping review. PLoS One. 2021; 16(5): e0251142. https://doi.org/10.1371/journal.pone.0251142</mixed-citation><mixed-citation xml:lang="en">Van der Scheer J.W., Totosy de Zepetnek J.O., Blauwet C., Brooke-Wavell K., Graham-Paulson T., Leonard A.N., et al. Assessment of body composition in spinal cord injury: A scoping review. PLoS One. 2021; 16(5): e0251142. https://doi.org/10.1371/journal.pone.0251142</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
