rospedРоссийский педиатрический журнал имени М.Я. СтуденикинаM.Ya. Studenikin Russian Pediatric JournalФГАУ «НМИЦ здоровья детей» Минздрава России10.46563/1560-9561-2023-26-1-75-78rosped-41Research ArticleКЛИНИЧЕСКИЙ СЛУЧАЙCLINICAL CASEОпыт ведения ребёнка с синдромом энтероколита, индуцированным пищевыми белками продуктов прикормаExperience in management of a child with enterocolitis syndrome induced by proteins from products of complementary foodshttps://orcid.org/0000-0002-3586-4031ГалицкаяМарина ГеннадьевнаGalitskayaMarina G.

Канд. мед. наук, ст. науч. сотр., Центр профилактической педиатрии ФГАУ «НМИЦ здоровья детей» Минздрава России.

e-mail: galitskaya.mg@nczd.ru

MD, PhD, senior researcher of the Department of preventive pediatrics of National Medical Research Center for Children’s Health, Moscow, 119991, Russian Federation.

e-mail: galitskaya.mg@nczd.ru 

galitskaya.mg@nczd.ruhttps://orcid.org/0000-0002-3056-403XМакароваСветлана ГеннадьевнаMakarovaSvetlana G.

Доктор мед. наук, зам. директора по научной работе, руководитель Центра профилактической педиатрии ФГАУ «НМИЦ здоровья детей» Минздрава России.

noemail@neicon.ruhttps://orcid.org/0000-0002-1650-652XЕрешкоОксана АлександровнаEreshkoOksana A.

Канд. мед. наук, ст. науч. сотр. Центра профилактической педиатрии ФГАУ «НМИЦ здоровья детей» Минздрава России.

noemail@neicon.ruhttps://orcid.org/0000-0001-6469-0766ЛебедеваАйина МихайловнаLebedevaAyina M.

Лаборант Центра профилактической педиатрии ФГАУ «НМИЦ здоровья детей» Мин­здрава России, аспирант ФГБУН «ФИЦ питания и биотехнологии».

noemail@neicon.ruФГАУ «Национальный медицинский исследовательский центр здоровья детей» Минздрава РоссииNational Medical Research Center for Children’s Health of the Ministry of Health of the Russian FederationФГАУ «Национальный медицинский исследовательский центр здоровья детей» Минздрава России; ФГБОУ ВО «Московский государственный университет им. М.В. Ломоносова»National Medical Research Center for Children’s Health of the Ministry of Health of the Russian Federation; M.V. Lomonosov Moscow State UniversityФГАУ «Национальный медицинский исследовательский центр здоровья детей» Минздрава России; ФГБУН «Федеральный исследовательский центр питания, биотехнологии и безопасности пищи»National Medical Research Center for Children’s Health of the Ministry of Health of the Russian Federation; Federal Research Centre of Nutrition, Biotechnology and Food Safety2023070920232617578Copyright © Галицкая М.Г., Макарова С.Г., Ерешко О.А., Лебедева А.М., 20232023Галицкая М.Г., Макарова С.Г., Ерешко О.А., Лебедева А.М.Galitskaya M.G., Makarova S.G., Ereshko O.A., Lebedeva A.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.rosped.ru/jour/article/view/41

В структуре аллергических болезней детей первых лет жизни синдром энтероколита, индуцированного пищевыми белками, занимает особое место. Это связано с трудностями его диагностики и схожестью клинической картины с симптомами других форм патологии органов пищеварения у детей. Чаще всего диагноз устанавливается по клинической картине и подтверждается положительной провокационной пробой с предполагаемым пищевым триггером. Авторами представлено описание синдрома энтероколита, индуцированного пищевыми белками, и приведён клинический случай синдрома у ребёнка 11 мес. Данный синдром был заподозрен на первом приёме врача диетолога-аллерголога после анализа клинической картины заболевания и подтверждён на повторном приёме через 1 мес. Показана роль провокационного введения причинно-значимого продукта в постановке диагноза, а также значимость элиминационной диеты для достижения ремиссии заболевания.

Участие авторов

Участие авторов:Галицкая М.Г., Ерешко ОА., Макарова С.Г. — концепция и дизайн исследования;Галицкая М.Г. — сбор и обработка медицинской документации;Галицкая М.Г., Ерешко О.А., Лебедева А.М. — написание текста;Макарова С.Г. — редактирование.Все соавторы — утверждение окончательного варианта статьи, ответственность за целостность всех частей статьи.

Финансирование

Финансирование. Исследование не имело финансовой поддержки.

Конфликт интересов

Конфликт интересов. Авторы заявляют об отсутствии конфликта интересов.

Поступила 08

Поступила 08.12.2022Принята к печати 17.01.2023Опубликована 28.02.2023

Enterocolitis syndrome induced by dietary proteins occupies a special place in the structure of allergic diseases in children of the first years of life. This is primarily due to the difficulties of diagnosing the syndrome, since there are currently no specific laboratory tests confirming the diagnosis, and the similarity of the clinical picture with the symptoms of other diseases of the gastrointestinal tract. Most often, the diagnosis is established according to the clinical picture and is confirmed by a positive provocative test with a suspected food trigger. The article briefly describes the enterocolitis syndrome induced by dietary proteins, and presents a clinical case of the syndrome in a child of 11 months. This syndrome was suspected at the first appointment of a nutritionist-allergist after analyzing the clinical picture of the disease and confirmed at a repeat appointment after 1 month. The significant role in the diagnosis by the provocative introduction of a causally significant product is shown, as well as the importance of prescribing an elimination diet to achieve remission of the disease.

Contribution

Contribution:Galitskaya M.G., Ereshko O.A., Makarova S.G. — research concept and design;Galitskaya M.G. — collection and analysis of data;Galitskaya M.G., Ereshko O.A., Lebedeva A.M. — writing the text;Makarova S.G. — editing.All co-authors — approval of the final version of the article, responsibility for the integrity of all parts of the article.

Acknowledgment

Acknowledgment. The study had no sponsorship.

Conflict of interest

Conflict of interest. The authors declare no conflict of interest.

Received

Received: December 08, 2022Accepted: January 17, 2023Published: February 28, 2023

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The authors declare that there are no conflicts of interest present.