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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rosped</journal-id><journal-title-group><journal-title xml:lang="ru">Российский педиатрический журнал имени М.Я. Студеникина</journal-title><trans-title-group xml:lang="en"><trans-title>M.Ya. Studenikin Russian Pediatric Journal</trans-title></trans-title-group></journal-title-group><publisher><publisher-name>ФГАУ «НМИЦ здоровья детей» Минздрава России</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.46563/1560-9561-2024-27-1-40-43</article-id><article-id custom-type="edn" pub-id-type="custom">ypeyhk</article-id><article-id custom-type="elpub" pub-id-type="custom">rosped-531</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>Экстракардиальная патология как дополнительный фактор риска при коррекции врождённых пороков сердца у детей</article-title><trans-title-group xml:lang="en"><trans-title>Extracardial pathology as an additional risk factor in the correction of congenital heart defects in children</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7512-3991</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сарсенбаева</surname><given-names>Гульжан Искендировна</given-names></name><name name-style="western" xml:lang="en"><surname>Sarsenbaeva</surname><given-names>Gulzhan I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Канд. мед. наук, кардиохирург, АО «Научный центр педиатрии и детской хирургии» Минздрава Республики Казахстан</p><p>e-mail: gulzhan75@mail.ru</p></bio><bio xml:lang="en"><p>MD, PhD, cardiac surgeon, Scientific Center of Pediatrics and Pediatric Surgery, Almaty, 050044, Republic of Kazakhstan</p><p>e-mail: gulzhan75@mail.ru</p></bio><email xlink:type="simple">gulzhan75@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>АО «Научный центр педиатрии и детской хирургии» Минздрава Республики Казахстан</institution></aff><aff xml:lang="en"><institution>Scientific Center of Pediatrics and Pediatric Surgery</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>04</day><month>04</month><year>2024</year></pub-date><volume>27</volume><issue>1</issue><fpage>40</fpage><lpage>43</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сарсенбаева Г.И., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Сарсенбаева Г.И.</copyright-holder><copyright-holder xml:lang="en">Sarsenbaeva G.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rosped.ru/jour/article/view/531">https://www.rosped.ru/jour/article/view/531</self-uri><abstract><sec><title>Введение</title><p>Введение. Сопутствующие заболевания при коррекции врождённых пороков сердца (ВПС) у детей являются значимыми факторами риска развития осложнений в послеоперационном периоде и актуальной проблемой детской кардиохирургии. В статье представлена роль коморбидности в детской кардиохирургии. Проведён сравнительный анализ клинических показателей кардиохирургического лечения пациентов с экстракардиальной патологией и без таковой.</p></sec><sec><title>Цель</title><p>Цель: определить значение экстракардиальной патологии как дополнительного фактора риска при коррекции ВПС у детей. </p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Проведён проспективный анализ 500 кардиохирургических пациентов, госпитализированных в отделение кардиохирургии и интервенционной кардиологии. Пациенты были распределены на группы с сопутствующей патологией (n = 350) и без сопутствующих болезней (n = 150). Использованы комплекс современных лечебных и диагностических процедур, мультидисциплинарный анализ.</p></sec><sec><title>Результаты</title><p>Результаты. Установлена высокая частота развития осложнений у больных основной группы (70%). Госпитальная летальность была увеличена у пациентов с сопутствующей патологией и составила 17,4% по сравнению с больными без сопутствующей патологии (3,3%). Средняя продолжительность пребывания в отделении реанимации и интенсивной терапии у пациентов с сопутствующей патологией составила 18 ± 2 койко-дня, у пациентов без сопутствующей патологии — 4 ± 2.</p></sec><sec><title>Заключение</title><p>Заключение. Наличие сопутствующей патологии у детей с ВПС существенно влияет на формирование осложнений и является прогностическим фактором риска, который необходимо включать в современные модели прогнозирования.</p></sec><sec><title>Финансирование</title><p>Финансирование. Исследование не имело финансовой поддержки.</p></sec><sec><title>Конфликт интересов</title><p>Конфликт интересов. Автор заявляет об отсутствии конфликта интересов.</p></sec><sec><title>Поступила 08</title><p>Поступила 08.12.2023Принята к печати 30.01.2024Опубликована 28.02.2024</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Concomitant diseases as a risk factor for surgery remain an urgent problem in pediatric cardiac surgery. The article presents the role of comorbidity in pediatric cardiac surgery. A comparative analysis of the indicators of cardiac surgical treatment of patients with and without extracardiac pathology was carried out. Aim: to determine the significance of extracardiac causes as an additional risk factor in the correction of congenital heart lesions in children.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. Prospective analysis of five hundred patients who had undergone cardiac surgery in the departments of cardiac surgery and interventional cardiology. Patients were divided into a main group of patients with concomitant pathology (n = 350) and a control group (n = 150) without concomitant pathology. A complex of modern therapeutic and diagnostic procedures and a multidisciplinary approach were used.</p></sec><sec><title>Results</title><p>Results. A high incidence of complications was shown in the main group (70%). Hospital mortality was higher in patients with concomitant pathology and amounted to 17.4%, compared to 3.3% in the group without concomitant pathology. The average duration in the ICU for patients with concomitant pathology was 18 ± 2 bed days, for patients without concomitant pathology — 4 ± 2 bed days.</p></sec><sec><title>Conclusion</title><p>Conclusion. The presence of concomitant pathology has been shown to influence significantly on the development of complications and be a prognostic risk factor that must be included in modern prediction models.</p></sec><sec><title>Acknowledgment</title><p>Acknowledgment. The study had no sponsorship.</p></sec><sec><title>Conflict of interest</title><p>Conflict of interest. The author declares no conflict of interest.</p></sec><sec><title>Received</title><p>Received: December 08, 2023Accepted: January 30, 2024Published: February 28, 2024</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>врождённые пороки сердца</kwd><kwd>детская кардиохирургия</kwd><kwd>сопутствующие и экстракардиальные заболевания</kwd></kwd-group><kwd-group xml:lang="en"><kwd>congenital heart defects</kwd><kwd>pediatric cardiac surgery</kwd><kwd>concomitant and extracardiac diseases</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Stoll C., Alembik Y., Roth M.P., Dott B., De Geeter B. Risk factors in congenital heart disease. Eur. J. Epidemiol. 1989; 5(3): 382–91. https://doi.org/10.1007/BF00144842</mixed-citation><mixed-citation xml:lang="en">Stoll C., Alembik Y., Roth M.P., Dott B., De Geeter B. Risk factors in congenital heart disease. Eur. J. 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