rospedРоссийский педиатрический журнал имени М.Я. СтуденикинаM.Ya. Studenikin Russian Pediatric JournalФГАУ «НМИЦ здоровья детей» Минздрава России10.46563/1560-9561-2021-24-5-348-355fkfsozrosped-915Research ArticleОБЗОРЫREVIEWSФакторы питания в патогенезе и лечении псориаза у детейNutritional factors in the pathogenesis and treatment of psoriasis in childrenМакароваСветлана ГеннадиевнаMakarovaSvetlana G.

Доктор мед. наук, руководитель центра профилактической педиатрии ФГАУ «НМИЦ здоровья детей»; проф. каф. многопрофильной клинической подготовки факультета фундаментальной медицины ФГБОУ ВО «МГУ им. М.В. Ломоносова»

e-mail: sm27@yandex.ru

sm27@yandex.ruПронинаИрина ЮрьевнаProninaIrina Yu.

Мл. науч. сотр. центра профилактической педиатрии, врач-диетолог, врач-эндокринолог

e-mail: krapchatovaiv@yandex.ru; pronina.iiu@nczd.ru

MD, junior researcher at Centre for Preventive Pediatrics, nutritionist, endocrinologist

e-mail: krapchatovaiv@yandex.ru; pronina.iiu@nczd.ru

krapchatovaiv@yandex.ruФГАУ «Национальный медицинский исследовательский центр здоровья детей»; ФГБОУ ВО «Московский государственный университет им. М.В. ЛомоносоваNational Medical Research Center for Children’s Health; Lomonosov Moscow State UniversityФГАУ «Национальный медицинский исследовательский центр здоровья детей»; ФГБУ «Национальный медицинский исследовательский центр эндокринологии» Минздрава РоссииNational Medical Research Center for Children’s Health; Endocrinology Research Centre202107102024245348355Copyright © Макарова С.Г., Пронина И.Ю., 20242024Макарова С.Г., Пронина И.Ю.Makarova S.G., Pronina I.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.rosped.ru/jour/article/view/915

Обзор посвящён анализу различных факторов питания в патогенезе псориаза. Определено значение как генетических, так и средовых факторов в механизмах формирования псориатической болезни. Авторы считают, что влияние питания на патогенетические звенья псориаза ещё недостаточно изучено и недооценивается. В клинических рекомендациях по ведению больных псориазом нет указаний на необходимость консультаций диетолога и использование диетических рекомендаций. Целью обзора является проведение анализа современных данных о значимости различных факторов питания в формировании псориатической болезни, патогенезе её осложнённого течения, а также эффективности диетических воздействий при лечении этой категории больных. Установлено, что изменения питания и использование биологически активных добавок к пище может иметь определённый эффект в комплексной терапии заболевания. Обсуждены возможности диетотерапии у пациентов с псориазом и метаболическим синдромом. Показано, что необходимо дальнейшее улучшение доказательной базы эффективности диетических методов в стратегии ведения больных псориазом, особенно пациентов детского возраста.

Участие авторов

Участие авторов: Макарова С.Г. — концепция, дизайн исследования, сбор и обработка материала, написание текста, редактирование;Пронина И.Ю. — сбор и обработка материала, написание текста, редактирование.Все авторы — утверждение окончательного варианта статьи, ответственность за целостность всех частей статьи.

Финансирование

Финансирование. Исследование не имело финансовой поддержки.

Конфликт интересов

Конфликт интересов. Авторы заявляют об отсутствии конфликта интересов.

Поступила 15

Поступила 15.10.2021Принята к печати 28.10.2021Опубликована 15.11.2021

 

 

In the pathogenesis of the psoriatic disease, genetic and environmental factors play a significant role, and one of the most critical ecological influences is nutrition. At the same time, the influence of nutrition on the pathogenetic links of psoriasis is currently underestimated. The clinical guidelines for managing children and adults with psoriasis do not mention the need to consult a nutritionist and any dietary recommendations. The purpose of this literature review was to analyze current data on the role of various nutritional factors in the development of psoriatic disease, the pathogenesis of its complicated course, as well as the effectiveness of dietary interventions in the treatment of this category of patients. The analysis of sixty eight sources of literature has shown that dietary changes and the use of biologically active food supplements can have a specific effect on the complex therapy of the disease. The possibilities of diet therapy in patients with psoriasis and metabolic syndrome are also discussed. At the same time, it is evident that further research is needed to improve the evidence base for the effectiveness of nutritional methods in managing this category of patients, especially in paediatric-age patients.

Contribution

Contribution: Makarova S.G. — concept, research design, collection and processing of material, text writing, editing; Pronina I.Yu. — collection and processing of material, text writing, editing. All co-authors — approval of the final version of the article, responsibility for the integrity of all parts of the article.

Acknowledgement

Acknowledgement. The study had no sponsorship.

Conflict of interest

Conflict of interest. The authors declare no conflict of interest.

Received

Received: October 15, 2021Accepted: October 28, 2021Published: November 15, 2021

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The authors declare that there are no conflicts of interest present.