Achievements and prospects in the prevention of food allergies
https://doi.org/10.46563/1560-9561-2025-28-1-74-78
EDN: knrtpo
Abstract
The review presents achievements and prospects in the prevention of food allergies (FA). The incidence of FA has increased worldwide, and this has determined the need to change approaches to the primary prevention of FA, which for a long time relied on elimination strategies in the diet of not only children, but also pregnant and lactating women.
The aim of the review is to determine the advantages of early introduction of highly allergenic foods as complementary foods for FA prevention.
Literature was searched in the following databases: PubMed, Embase, Cochrane Library, Google. For children at high risk of developing FA, there is convincing evidence of the benefits of early administration of allergenic foods, in particular peanuts and eggs. It is believed that in such cases, not only should these products not be delayed, but they should be administered around the age of 4–6 months to minimize the risk of developing FA. All current guidelines recommend this approach regardless of the risk of developing FA.
Conclusion. Taking into account the trends towards the early introduction of allergenic products as a prevention of FA, it can be argued that a significant transition has been made from an elimination strategy to a strategy for the formation of tolerance to food allergens.
Contribution:
Larkova I.A. — research concept and design of the study, collection and processing of the material, writing the text;
Revyakina V.A. — science editing the text.
All co-authors — approval of the final version of the article, responsibility for the integrity of all parts of the article.
Acknowledgment. This work was carried out within the framework of the implementation of the topic of the state assignment of the Federal Research Center of Nutrition and Biotechnology No. FGMF-2023-0008 «Development of medical technologies for the diagnosis and correction of malnutrition in patients with non-infection diseases».
Conflict of interest. The authors declare no conflict of interest.
Received: January 16, 2025
Accepted: January 30, 2025
Published: February 28, 2025
About the Authors
Inna A. Larkova
Federal Research Center for Nutrition, Biotechnology, and Food Safety; National Medical Research Center for Children’s Health
Russian Federation
Russian Federation
MD, PhD., senior researcher, Allergy department, Federal Research Center for Nutrition, Biotechnology, and Food Safety, Moscow, 109240, Russian Federation; senior researcher, lab. of immunology and nutrition of the Center for Preventive Pediatrics National Medical Research Centre for Children’s Health, Moscow, 119991, Russian Federation
e-mail: inna_larkova@mail.ru
Vera A. Revyakina
Federal Research Center for Nutrition, Biotechnology, and Food Safety; National Medical Research Center for Children’s Health
Russian Federation
Russian Federation
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Review
For citations:
Larkova I.A., Revyakina V.A. Achievements and prospects in the prevention of food allergies. Russian Pediatric Journal. 2025;28(1):74-78. (In Russ.) https://doi.org/10.46563/1560-9561-2025-28-1-74-78. EDN: knrtpo
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