Хроническая сердечная недостаточность у детей: этиология, патогенез, клиника и диагностика

Хроническая сердечная недостаточность (ХСН) является грозным осложнением заболеваний сердечно-сосудистой системы или её поражений при других формах патологии и характеризуется значительным риском инвалидизации и смертности. В основе прогрессирования ХСН любой этиологии лежит ремоделирование сердечно-сосудистой системы, связанное с активацией нейрогормональных систем: симпатико-адреналовой (САС) и ренин-ангиотензин-альдостероновой (РААС). Цель обзора: представить современные концепции этиологии, патогенеза, диагностики и клинической картины ХСН у детей для оптимизации клинического ведения больных и расширения объёма знаний практикующих врачей. Современным фармакологическим методом лечения, влияющим на прогноз, предупреждающим прогрессирование поражения миокарда, является модулирование активности САС и РААС на циркуляторном, тканевом и клеточном уровнях. При определении тактики лечения детей следует установить этиологию ХСН, идентифицировать сопутствующие формы патологии, определить варианты и степень выраженности дисфункции миокарда, оценить тяжесть клинических проявлений.

Участие авторов:
Басаргина Е.Н. — концепция и дизайн исследования;
Васичкина Е.С., Жарова О.П., Ковалев И.А., Колоскова Н.Н., Котлукова Н.П., Леонтьева И.В., Первунина Т.М., Рябцев Д.В., Сильнова И.В., Трунина И.И. — сбор и обработка материала;
Басаргина Е.Н., Котлукова Н.П., Жарова О.П., Трунина И.И. — написание текста;
Басаргина Е.Н., Васичкина Е.С., Ковалев И.А. — редактирование.
Все соавторы — утверждение окончательного варианта статьи, ответственность за целостность всех частей статьи.

Финансирование. Исследование не имело финансовой поддержки.

Конфликт интересов. Авторы заявляют об отсутствии конфликта интересов.

Поступила 23.04.2025
Принята к печати 20.05.2025
Опубликована 27.06.2025

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