Features of determining the diffusion capacity of the lungs by carbon monoxide in cystic fibrosis children
https://doi.org/10.46563/1560-9561-2022-25-5-350-356
EDN: eybiha
Abstract
The article presents current literature data from English-language (search made in PubMed) and Russian-language (search made in eLibrary) sources about the method for measurement of the lung diffusing capacity for carbon monoxide in children with cystic fibrosis (CF). This review presents the general characteristics of this test in children and adults with various diseases, and also describes the conflicting results of studies using this method in CF patients of various ages and disease severity. The expediency, the informativeness, and difficulties of evaluation and interpretation of the test’s results, depending on the age and course of the disease of patients, are discussed. The author concludes that further research of interpretation of indicators determined during the test of the lung diffusing capacity for carbon monoxide, such as the transfer factor, alveolar volume, and their ratio in CF children is necessary.
Acknowledgment. The study had no sponsorship.
Conflict of interest. The author declares no conflict of interest.
Received: August 24, 2022
Accepted: September 20, 2022
Published: October 31, 2022
About the Author
Serafima G. Bystrova
I.M. Sechenov First Moscow State Medical University (Sechenov University); National Medical Research Center for Children’s Health, Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
MD, PhD student in the Department of Pediatrics and Pediatric Rheumatology, N.F. Filatov Clinical Institute of Children’s Health, I.M. Sechenov First Moscow State Medical University (Sechenov University), assistant in the Laboratory of childhood rare genetic diseases, National Medical Research Center for Children’s Health, Ministry of Health of the Russian Federation.
e-mail: cerafima.bystrova@yandex.ru
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For citations:
Bystrova S.G. Features of determining the diffusion capacity of the lungs by carbon monoxide in cystic fibrosis children. Russian Pediatric Journal. 2022;25(5):350-356. (In Russ.) https://doi.org/10.46563/1560-9561-2022-25-5-350-356. EDN: eybiha
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