Особенности полового развития девочек-подростков с муковисцидозом

Обзор посвящён актуальной и недостаточно изученной проблеме — особенностям полового развития девочек-подростков с муковисцидозом, срокам становления менархе, отклонениям в этапах пубертатного периода, анатомо-физиологическим особенностям женской репродуктивной системы при данном моногенном заболевании. Увеличение продолжительности жизни, а также распространение и повышение доступности таргетной терапии определяет необходимость дальнейших исследований данной темы. Ранняя диагностика нарушения полового развития за счёт своевременно назначенной терапии (гормональной) позволяет не только корригировать сроки наступления менархе у девочек-подростков с муковисцидозом, но и увеличить шансы зачатия и вынашивания ребёнка.

Участие авторов:
Горяинова А.В., Караченцова И.В., Сибирская Е.В., Шарков С.М. — концепция и дизайн исследования;
Горяинова А.В., Голубкова В.М., Бондаренко О.В., Караченцова И.В. — сбор и обработка материала, написание текста;
Бондаренко О.В., Голубкова В.М., Караченцова И.В. — редактирование.
Все соавторы — утверждение окончательного варианта статьи, ответственность за целостность всех частей статьи.

Финансирование. Исследование не имело финансовой поддержки.

Конфликт интересов. Авторы заявляют об отсутствии конфликта интересов. 

Поступила 16.06.2022
Принята к печати 29.06.2022
Опубликована 30.08.2022

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