Diagnostics of hamartomal polyps of the deep sections of the small intestine in children with Peutz–Jeghers syndrome and juvenile polyposis

Introduction. Peutz–Jeghers syndrome (PJS) and juvenile polyposis (JP) are congenital, inherited polyposis of the gastrointestinal tract. Both diseases are rare and characterized by the development of polyps in the small intestine, which can cause small intestine intussusception, obstruction of the gastrointestinal tract, and perforation of the intestinal wall. The main method of treatment is surgical. Polyps are formed throughout the life, and most patients undergo many surgical interventions, but despite this, there is currently no unequivocal opinion on the effectiveness of diagnostic and monitoring methods.

The purpose of this study is to determine the effectiveness of balloon enteroscopy, ultrasound examination of the abdominal cavity and video capsule enteroscopy as methods for diagnosing hamartoma polyps of the deep sections of the small intestine in children with Peutz–Jeghers syndrome and juvenile polyposis.

Materials and methods. Twenty seven SPE and JP patients were examined. Over the period from 2018 to 2022, this group of patients was hospitalized 67 times. Each hospitalization was assessed as a separate case. The average age at the first visit to medical care was 11 years 3 months. (min — 3 years, 6 months, max — 17 years 10 months). All patients underwent abdominal ultrasound and balloon enteroscopy (BE), 7 patients underwent video capsule enteroscopy (VCE).

Results. In 24 cases, ultrasound revealed intussusception of the small intestine. BE revealed 236 polyps in the small intestine, including 29 giant ones. 7 VCE revealed 57 polyps, while BE revealed 30 polyps in the same patients.

Conclusion. Ultrasound of the abdominal cavity does not reveal polyps of the small intestine, but is able to determine the presence of intussusceptum. VCE is the most effective method for detecting polyps, however, BE allows not only searching, but also radical removing.

Contribution:
Korolev G.A., Lokhmatov M.M., Dyakonova E.Yu. — the concept and design of the study;
Korolev G.A., Budkina T.N., Oldakovskiy V.I., Tupylenko A.V., Khazykova D.V., Bekin A.S. — collection and processing of material, writing the text, editing the text.
All co-authors — approval of the final version of the article, responsibility for the integrity of all parts of the article.

Acknowledgment. The study had no sponsorship.

Conflict of interest. The authors declare no conflict of interest.

Received: May 24, 2023
Accepted: June 20, 2023
Published: August 31, 2023

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