Features of pubertal development of adolescent girls with cystic fibrosis
Anastasia V. Goryainova,
Irina V. Karachentsova,
Elena V. Sibirskaya,
Sergey M. Sharkov,
Varvara M. Golubkova,
Olesya V. Bondarenko https://doi.org/10.46563/1560-9561-2022-25-4-230-235
EDN: lcgetg
Abstract
This review is devoted to an urgent and insufficiently studied problem — the characteristics of the pubertal development of girls with cystic fibrosis (CF), the deviations in the period of menarche, the stages of the puberty, anatomical and physiological features of the female reproductive system in this monogenic disease. The increase in life expectancy, as well as the spread and increasing availability of targeted therapies, highlight the need for further research on this topic. Early diagnosis of disorders of pubertal development due to timely prescribed therapy (hormonal) allows not only correcting the timing of the onset of menarche in CF adolescent girls, but also increasing the chances of conceiving and bearing a child.
Contribution:
Goryainova A.V., Karachentsova I.V., Sibirskaya E.V., Sharkov S.M. — research concept and design of the study;
Goryainova A.V., Golubkova V.M., Bondarenko O.V., Karachentsova I.V. — collection and processing of material;
Goryainova A.V., Golubkova V.M., Bondarenko O.V., Karachentsova I.V. — text writing;
Bondarenko O.V., Golubkova V.M., Karachentsova I.V. — editing.
All co-authors — approval of the final version of the article, responsibility for the integrity of all parts of the article.
Acknowledgment. The study had no sponsorship.
Conflict of interest. The authors declare no conflict of interest.
Received: June 16, 2022
Accepted: June 29, 2022
Published: 30 August, 2022
About the Authors
Anastasia V. Goryainova
Russian Children’s Clinical Hospital, Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Irina V. Karachentsova
Russian Children’s Clinical Hospital, Pirogov Russian National Research Medical University; Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
MD, PhD, Associate Professor of the Department of Obstetrics and Gynecology, Faculty of Pediatrics, Pirogov Russian National Research Medical University, 119571, Moscow, Russian Federation; obstetrician-gynecologist of the surgical gynecological department of Russian Children’s Clinical Hospital, Pirogov Russian National Research Medical University, 119571, Moscow, Russian Federation.
e-mail: 5053104@list.ru
Elena V. Sibirskaya
Russian Children’s Clinical Hospital, Pirogov Russian National Research Medical University; Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Russian Federation
Russian Federation
Sergey M. Sharkov
Morozov Children Municipal Clinical Hospital; I.M. Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
Varvara M. Golubkova
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Olesya V. Bondarenko
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
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Goryainova A.V., Karachentsova I.V., Sibirskaya E.V., Sharkov S.M., Golubkova V.M., Bondarenko O.V. Features of pubertal development of adolescent girls with cystic fibrosis. Russian Pediatric Journal. 2022;25(4):230-235. (In Russ.) https://doi.org/10.46563/1560-9561-2022-25-4-230-235. EDN: lcgetg
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