The effect of optimizing the nutrition in premature infants with bronchopulmonary dysplasia on their body composition and nutritional status
https://doi.org/10.46563/1560-9561-2024-27-2-103-110
Abstract
Aim: To study the effect of the inclusion of MCT in the nutrition of premature BPD infants on their nutritional and anthropometric status.
Materials and methods. There were examined 75 BPD premature infants, divided in 2 groups: main (n = 49) — infants receiving a fat module with nutrition, represented by 100% medium-chain triglycerides (SCT); control (n = 26) — infants received no SCT. Before the start, 1 month and 4 months after the beginning of the study, the quantitative content of biochemical indices characterizing protein and fat metabolism was determined. 1 month and 4 months after the beginning of the study, the examination of body composition (indices of fat and fat-free mass), as well as residual lung capacity, was carried out on a PeaPod analyzer, LMi, USA.
Results. An increase in fat content in diets and their caloric content, even against the background of dietary restrictions in BPD infants, provided positive trend in anthropometric indices, a gain in the amount of lean mass without excessive accumulation of body fat and an increase in lung volume.
About the Authors
Milana A. BasarginaRussian Federation
Andrey P. Fisenko
Russian Federation
Vera A. Skvortsova
Russian Federation
Tatyana E. Borovik
Russian Federation
Mariya S. Illarionova
Russian Federation
Evgeniya L. Pinaeva-Slysh
Russian Federation
Nataliya A. Kharitonova
Russian Federation
References
1. Rocha G., Guimarães H., Pereira-da-Silva L. The role of nutrition in the prevention and management of bronchopulmonary dysplasia: A literature review and clinical approach. Int. J. Environ. Res. Public Health. 2021; 18(12): 6245. https://doi.org/10.3390/ijerph18126245
2. Программа оптимизации вскармливания детей первого года жизни в Российской Федерации: Методические рекомендации. М.; 2019.
3. Скворцова В.А., Давыдова И.В., Фисенко А.П., Пинаева-Слыш Е.Л., Боровик Т.Э., Басаргина М.А. и др. Особенности нутритивного статуса недоношенных детей с бронхолегочной дисплазией в первом полугодии жизни. Педиатрия. Журнал им. Г.Н. Сперанского. 2021; 100(4): 161–70. https://doi.org/10.24110/0031-403X-2021-100-4-161-170 https://elibrary.ru/wdxjio
4. Белоусова Т.В., Скворцова В.А., Андрюшина И.В. Диспансерное наблюдение на педиатрическом участке за детьми, родившимися недоношенными: методическое пособие для врачей педиатров. М.; 2021.
5. Miliku K., Duan Q.L., Moraes T.J., Becker A.B., Mandhane P.J., Turvey S.E., et al. Human milk fatty acid composition is associated with dietary, genetic, sociodemographic, and environmental factors in the CHILD cohort study. Am. J. Clin. Nutr. 2019; 110(6): 1370–83. https://doi.org/10.1093/ajcn/nqz229
6. Malikiwi A.I., Lee Y.M., Davies-Tuck M., Wong F.Y. Postnatal nutritional deficit is an independent predictor of bronchopulmonary dysplasia among extremely premature infants born at or less than 28 weeks gestation. Early Hum. Dev. 2019; 131: 29–35. https://doi.org/10.1016/j.earlhumdev.2019.02.005
7. Савва Н.Н., Овсянников Д.Ю., Жесткова М.А. Бронхолегочная дисплазия: Медицинское сопровождение на дому. М.: Проспект; 2020.
8. Овсянников Д.Ю., Геппе Н.А., Малахов А.Б., Дегтярева Д.Н., ред. Бронхолегочная дисплазия. М.; 2020.
9. Santoro K., Martin C.R. Lipids and long chain polyunsaturated fatty acids in preterm infants. Clin. Perinatol. 2022; 49(2): 381–91. https://doi.org/10.1016/j.clp.2022.02.007
10. Yuan T., Wang L., Jin J., Mi L., Pang J., Liu Z., et al. Role medium-chain fatty acids in the lipid metabolism of infants. Front. Nutr. 2022; 9: 804880. https://doi.org/10.3389/fnut.2022.804880
11. Sahin S., Ozdemir T., Katipoglu N., Akcan A.B., Kaynak Turkmen M. Comparison of changes in breast milk macronutrient content during the first month in preterm and term infants. Breastfeed. Med. 2020; 15(1): 56–62. https://doi.org/10.1089/bfm.2019.0141
12. Володина Н.Н., Дегтярева Д.Н., ред. Неонатология: национальное руководство. Том 1. М.: ГЭОТАР-Медиа; 2023.
13. Hahn W.H., Song J.H., Song S., Kang N.M. Do gender and birth height of infant affect calorie of human milk? An association study between human milk macronutrient and various birth factors. J. Matern. Fetal. Neonatal. Med. 2017; 30(13): 1608–12. https://doi.org/10.1080/14767058.2016.1219989
14. Клинические рекомендации «Энтеральное вскармливание недоношенных детей». M.; 2015.
15. Embleton N.D., Moltu J.S., Lapillonne A., van den Akker C.H.P., Carnielli V., Fusch C., et al. Enteral nutrition in preterm infants (2022): A position paper from the ESPGHAN Committee on nutrition and invited experts. J. Pediatr. Gastroenterol. Nutr. 2023; 76(2): 248–68. https://doi.org/10.1097/MPG.0000000000003642
16. Simon L., Borrego P., Darmaun D., Legrand A., Rozé J.C., Chauty-Frondas A. Effect of sex and gestational age on neonatal body composition. Br. J. Nutr. 2013; 109(6): 1105–8. https://doi.org/10.1017/S0007114512002991
17. Belfort M., Cherkerzian S., Bell K., Soldateli B., Cordova R.E., Palmer C., et al. Macronutrient intake from human milk, infant growth, and body composition at term equivalent age: A longitudinal study of hospitalized very preterm infants. Nutrients. 2020; 12(8): 2249. https://doi.org/10.3390/nu12082249
18. Davis S.M., Kaar J.L., Ringham B.M., Hockett C.W., Glueck D.H., Dabelea D. Sex differences in infant body composition emerge in the first 5 months of life. J. Pediatr. Endocrinol. Metab. 2019; 32(11): 1235–9. https://doi.org/10.1515/jpem-2019-0243
19. Carnielli V.P., Sulkers E.J., Moretti C., Wattimena J.L., van Goudoever J.B., Degenhart H.J., et al. Conversion of octanoic acid into long-chain saturated fatty acids in premature infants fed a formula containing medium-chain triglycerides. Metabolism. 1994; 43(10): 1287–92. https://doi.org/10.1016/0026-0495(94)90224-0
Review
For citations:
Basargina M.A., Fisenko A.P., Skvortsova V.A., Borovik T.E., Illarionova M.S., Pinaeva-Slysh E.L., Kharitonova N.A. The effect of optimizing the nutrition in premature infants with bronchopulmonary dysplasia on their body composition and nutritional status. Russian Pediatric Journal. 2024;27(2):103-110. (In Russ.) https://doi.org/10.46563/1560-9561-2024-27-2-103-110