Endocytoscopy in the diagnosis of rare forms of esophagitis in the child
Anastasiya O. Merkulova,
Anastasiya Yu. Kharitonova,
Andrey A. Shavrov,
Egor A. Frolov,
Vitaliy A. Kapustin,
Anton A. Shavrov,
Vsevolod V. Stolyarov,
Olga V. Karaseva https://doi.org/10.46563/1560-9561-2025-28-4-293-298
Abstract
Introduction. Eosinophilic and herpetic esophagitis are difficult for diagnosis. Moreover, their combination in immunocompetent children is rare. Aim. To present a clinical report on a combination of rare forms of esophagitis in the child and the role of endocytoscopy in the diagnosis of these conditions.
Materials and methods. A clinical case of herpetic and eosinophilic esophagitis in a 16-year boy with complaints of dysphagia and severe odynophagia is presented.
Results. At the esophagogastroduodenoscopy (EGD) and endocytoscopy with optical magnification up to 520× virus esophagitis was suspected. Histological examination of the mucosal biopsy and blood polymerase chain reaction (PCR) confirmed herpes virus types 1 and 2. In 3 months after the treatment, follow-up EGD with endocytoscopy revealed endomicroscopic signs of eosinophilic esophagitis (EoE). The patient was prescribed a proper therapy.
Conclusion. Modern endoscopic technologies, such as endocytoscopy, improve diagnosis, determine the volume and effectiveness of therapy of these esophageal lesions in children.
Materials and methods. A clinical case of herpetic and eosinophilic esophagitis in a 16-year boy with complaints of dysphagia and severe odynophagia is presented.
Results. At the esophagogastroduodenoscopy (EGD) and endocytoscopy with optical magnification up to 520× virus esophagitis was suspected. Histological examination of the mucosal biopsy and blood polymerase chain reaction (PCR) confirmed herpes virus types 1 and 2. In 3 months after the treatment, follow-up EGD with endocytoscopy revealed endomicroscopic signs of eosinophilic esophagitis (EoE). The patient was prescribed a proper therapy.
Conclusion. Modern endoscopic technologies, such as endocytoscopy, improve diagnosis, determine the volume and effectiveness of therapy of these esophageal lesions in children.
About the Authors
Anastasiya O. Merkulova
Clinical and Research Institute of Emergency Pediatric Surgery and Trauma — Dr. Roshal’s Clinic
Russian Federation
Russian Federation
Anastasiya Yu. Kharitonova
Clinical and Research Institute of Emergency Pediatric Surgery and Trauma — Dr. Roshal’s Clinic
Russian Federation
Russian Federation
Andrey A. Shavrov
Clinical and Research Institute of Emergency Pediatric Surgery and Trauma — Dr. Roshal’s Clinic
Russian Federation
Russian Federation
Egor A. Frolov
Clinical and Research Institute of Emergency Pediatric Surgery and Trauma — Dr. Roshal’s Clinic
Russian Federation
Russian Federation
Vitaliy A. Kapustin
Clinical and Research Institute of Emergency Pediatric Surgery and Trauma — Dr. Roshal’s Clinic
Russian Federation
Russian Federation
Anton A. Shavrov
University Children’s Clinical Hospital, Sechenov Center for Motherhood and Childhood
Russian Federation
Russian Federation
Vsevolod V. Stolyarov
Morozov Children’s Municipal Clinical Hospital of the Department of Health of Moscow
Russian Federation
Russian Federation
Olga V. Karaseva
Clinical and Research Institute of Emergency Pediatric Surgery and Trauma — Dr. Roshal’s Clinic
Russian Federation
Russian Federation
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Review
For citations:
Merkulova A.O., Kharitonova A.Yu., Shavrov A.A., Frolov E.A., Kapustin V.A., Shavrov A.A., Stolyarov V.V., Karaseva O.V. Endocytoscopy in the diagnosis of rare forms of esophagitis in the child. Russian Pediatric Journal. 2025;28(4):293-298. (In Russ.) https://doi.org/10.46563/1560-9561-2025-28-4-293-298
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