Continuously Recurring Entero-Enteric Intussusception in a Child with Peutz‒Jeghers Syndrome

Peutz‒Jeghers syndrome is a rare hereditary disorder characterized by hamartomatous gastrointestinal polyps and mucocutaneous pigmentation. In childhood, the most clinically significant complications are intussusception and chronic blood loss leading to anemia.
We present a case of a 12-year-old boy with clinically verified Peutz‒Jeghers syndrome, burdened family history, marked pigmentation of the lips and oral mucosa, multiple hamartomatous gastrointestinal polyps, and mild anemia. During planned hospitalization, despite the absence of clinical signs of acute intestinal obstruction, abdominal ultrasound revealed intussusception associated with a polyp. At the first stage, retrograde balloon enteroscopy and endoscopic polypectomy were performed. Follow-up ultrasound demonstrated persistent entero-enteric intussusception, which determined the need for urgent surgical treatment. Laparoscopic desinvagination, enterotomy and polypectomy without bowel resection were performed. Histological examination confirmed hamartomatous polyps. The postoperative period was uneventful. 
This case demonstrates that even in minimally symptomatic Peutz‒Jeghers syndrome, ultrasound monitoring plays a key role in detecting continuously recurring intussusception and in choosing a stage-based treatment strategy.

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